For a long time, the relationship between cannabis use and psychosis has been a hot topic of debate. As cannabis continues to gain acceptance and legalisation across the globe, it’s crucial to have a clear understanding of its effects.
A groundbreaking study has recently emerged, challenging some long-held beliefs regarding the connection between cannabis use and psychosis.
The authors of this new study took a meticulous approach to explore the relationship between cannabis use and the incidence of psychotic disorders in individuals considered to be at high risk of psychosis. They assessed the current and past cannabis use of over 300 individuals, along with 67 healthy participants.
For two years, all participants were closely monitored and assessed using the Global Assessment of Functioning disability scale and the Comprehensive Assessment of At-Risk Mental States criteria. This was to evaluate transitions to psychosis and the persistence of psychotic symptoms.
According to the study, 16.2% of the high-risk sample developed psychosis during the follow-up. Among those who did not become psychotic, 51.4% experienced persistent symptoms, while 48.6% went into remission. Interestingly, the study found no significant association between cannabis use and either transition to psychosis, persistence of symptoms, or functional outcome.
Contrasting Findings and Global Implications
This study’s findings are particularly noteworthy as they contradict previous epidemiological data, which suggested that cannabis use heightened the risk of developing psychotic disorders.
Past research considered factors such as THC potency, frequency of use, and the age and genetics of the consumer in relation to the risk of developing psychosis.
The United States, where cannabis legalisation is on the rise, also offers valuable insights.
A paper published by researchers from the Hospital of the University of Pennsylvania examined claims data from over 63 million individuals and discovered no statistically significant difference in psychosis-related diagnoses in states with medical or recreational cannabis policies compared to those where cannabis remains prohibited.
Adding Layers of Evidence: The Twin Study
Adding to the body of evidence, a 2021 study investigated the relationship between adolescent cannabis use and adult-onset psychosis through a longitudinal co-twin control analysis.
This study found no dose-response relationship or discernible differences in the effects of cannabis exposure on the risk of developing schizophrenia later in life.
Towards a Clearer Understanding
This groundbreaking research brings much-needed clarity to the ongoing debate around cannabis use and psychosis. It challenges the mainstream narrative and provides a fresh perspective on the subject.
While it’s important to continue researching and understanding the complexities of cannabis use, this study is a significant stride in the right direction.
